Zydus Research Centre Walk In Interview For Multiple Opening

Zydus Research Centre Walk In Interview For Multiple Opening

Inviting candidates for a walk-in interview for multiple openings at Zydus Research Centre, Ahmedabad on 7th January, 2024 from 8 am to 4.30 pm (The interview will take place at Bengaluru)


1) Protein Characterization Mass Spectrometry : Ph. D / M.Sc. / M. Tech. (Biochemistry / Biotechnology) with at least 2-8 years of industrial hands-on experience in protein characterization by mass spectrometry. Sound knowledge in mass spectrometry-based analysis of protein molecules e.g., antibodies (preferred), peptides, DNA / RNA etc with scientific report writing skills.

Analytical : M.Sc. / M. Tech. (Biochemistry / Biotechnology) with at least 5 years of industrial hands-on experience in protein characterization including HPLC, structural, and biochemical techniques. Sound knowledge in analytical method development, validation, technology transfer activity and scientific report writing skills.

QMS : M.Sc. / M. Tech. (Biochemistry / Biotechnology / Life sciences) with 0 - 4 years of experience in protein analytics, such as HPLC, structural, biochemical, ELISA, mass spectrometry and electrophoretic techniques OR Biologics QA experience in quality management systems (QMS) and compliance. Good communication and report writing skills.



Upstream Process : M.Sc. (Microbiology / Biochemistry / Biotechnology) / M. Tech. in Biotechnology with 1-3 years of hands-on experience in upstream operations like handling mammalian cell culture process and microbial fermentation. Handling equipment such as Bioreactors, CEDEX Bioanalyzer, etc., candidates should be capable of performing activities such as handling of mammalian cell lines, cell bank preparation, media scouting and process optimization at shake flasks, small-scale bioreactors and pilot scale bioreactors to improve yields & product quality. Should have good documentation skills like SOP, STP etc.

Upstream Process : Ph.D., (Microbiology / Biochemistry / Biotechnology) / M. Tech. in Biotechnology with more than 10 years of experience. Candidates should have hands-on experience in upstream process development and process characterization of mammalian and microbial culture. Sound scientific knowledge as well as report writing skills like Process Development Report, Technology Transfer Document and scale up. Should have proven track record to lead a sizeable team.

Downstream processing and Antibody drug conjugate : PhD / M.Sc. / M. Tech. (Biochemistry / Biotechnology / Life sciences) with 2 - 8 years of hands-on experience in protein purification techniques like centrifugation, depth filtration, lab scale column purification, ultrafiltration / diafiltration. Handling of equipment such as AKTA Avant, AKTA Pure, AKTA Pilot, Automatic TFF system, High throughput screening system, Isolator, Membrane chromatography. Candidates should be capable of performing activities such as resin screening and process optimization for Mab and ADC at small-scale and pilot scale. Good communication and documentation (SOP / BMR / TTD / purification report) skills etc


Down Stream Process : PhD / M. Tech. / M.Sc. (Biochemistry / Biotechnology / Life sciences / Biochemical Engineering) with more than 10 years of experience. Hands-on experience with Downstream process development for mammalian and microbial process. Sound scientific knowledge as well as report writing skills like Process Development Report and Technology Transfer Document. Should have proven track record to lead a sizeable team.

In-process analysis and stability group : Ph.D., M.Sc., M. Tech, M. Pharm Biotechnology / Biochemistry or equivalent with 3-10 years of experience. Candidates should have hands-on experience in HPLC, gel electrophoresis, spectrophotometric, structural and biochemical techniques for biosimilar or novel biological products. Candidates would be responsible for development and qualification of analytical methods, in-process analysis during upstream, downstream and drug product process development, degradation / stability studies, excipient analysis, report and protocol writing.

Formulations Group : Ph.D., M.Sc., M. Tech in Biotechnology / Biochemistry or M. Pharm Biotechnology / Pharmaceutics with 3-5 Years of experience. Candidates would be responsible for planning and execution of formulation development, stability / degradation studies and technology transfer for biosimilar and novel biological products. Candidate should have hands-on experience on techniques related to liquid and lyophilized formulation development. Candidates would also be responsible for formulation screening studies, selection of container-closure systems, analysis for formulation screening studies, stability / degradation studies and documentation, drug product manufacturing technology transfer activities to the manufacturing site including execution of the drug product batch manufacturing in collaboration with manufacturing team.



2) Cell line development, Cell and Gene therapy, Immunoanalytics

Molecular Biology : M. Sc. in any field of life sciences with 3-4 years of experience / Ph.D. in life sciences with hands on experience in molecular biology techniques like PCR, Real-time PCR, Nucleic acid isolation, rDNA techniques, DNA sequencing, in-vitro transcription and in-vitro translation and basic DNA / RNA / Protein analytic tools. Basic knowledge of bioinformatics to handle Molecular Biology analysis tools. Experience in cell and gene therapy development activities like LV / AAV / RV vector constructions, and molecular biology based engineered viral vector and cell characterization. Candidates are required to have good communication and scientific report writing skills.

Mammalian cell culture : M.Sc.(Any Life sciences area) / M. tech / M. Pharm with Biotechnology – Freshers or candidates with 3-5 years of experience in mammalian cell culture such as handling of various cell lines, optimization & execution of stable / transient transfections, clone screening, media / process optimization at shake flasks & small scale bioreactors to improve yields & quality, cell bank preparations, ELISAs. Basic understanding of DoE tools for media optimizations. Should have experience in cell and gene therapy development activities like LV / RV / AAV production, Primary cells (Stem cells / T cells / NK cells etc) isolation and expansion, cytotoxicity assays, etc.

Upstream analytics : M.Sc. (Any Life sciences area) / M. Tech (Biochemistry / Biotechnology) / M. Pharm –with Biotechnology. Freshers or candidates with 2-4 years of experience in protein binding studies using SPR; purification of therapeutic proteins, antibodies, LVs / AAVs / RVs etc., protein characterization techniques like HPLC, HP-SEC, IEF, IEC, SDS PAGE etc., for characterization of Biologics.


(Immunoassays) PK / PD / Immunogenicity : MSc. (Any life sciences area) / M. Pharm (Biotechnology / Pharmacology)- Freshers or candidates with 3-7 years of experience in activities like development, validation & execution of PK / PD / Immunogenicity / Nab assays (ELISA / CLIA / MSD) to support pre-clinical & clinical studies for Biosimilar / New Biologics in a GLP set up, experience in animal handling, preparation of regulatory documents. Candidates should have scientific understanding of PK / PD / ADA of biologics in animals & humans; knowledge of biostatistics, animal to human dose simulations etc.

Bioassay : Ph. D / M.Sc. / M. Tech. (Biochemistry / Biotechnology) with at least 3 years of practical laboratory experience in development of immunoassays like CDC (complement dependent cytotoxicity), ADCC (antibody dependent cell cytotoxicity), ADCP (Antibody dependent Cell Phagocytosis) and Apoptosis assays. Candidates should have a background in other immunoassay method development such as ELISA, bioassays with a particular emphasis on flow cytometry. An ability to define and prioritize key parameters that help in successful conceptualization of assays and projects. They should exhibit strong organizational skills, with an ability to work effectively within deadlines and should have good verbal and written communication skills.

Novel Biologics : PDF / Ph.D. / MSc. (Biotechnology) candidates with 2-7 years of experience in activities like molecular cloning, protein expression and purification, literature review for novel target and hands on experience in documentation.

Venue : Starlit Suites Bengaluru, No E39/275, Smondo Complex, Neo Town, Near Fire Bridge, Electronic City, Bengaluru, Karnataka 560100 · 080 4340 3333